Choroidal melanomata. Fluorescence angiographic and histopathological study.

This clinico-pathological study has been carried out on benign and malignant choroidal melanomata with the following objects in view: (I) To find out the fluorescent pattern on fluorescence angiography which would distinguish a pigmented choroidal malignant melanoma from other lesions of similar appearance in the fundus of the eye, e.g. pigmented benign choroidal melanoma or nonneoplastic pigmentation. (2) To study the pattern in non-pigmented malignant choroidal melanomata which could be confused with choroidal haemangiomata. (3) To find out the pathological basis of the fluorescent pattern seen in benign and malignant choroidal melanomata. (4) To find out the true nature of a benign choroidal melanoma, i.e. whether the pigmentation is always clioroidal or is due in some cases to hyperplasia of the pigment epithelium.